Researchers found that CBD reduces cocaine dependency in mice.
Treating cocaine addiction is a complicated process that doesn't have any clear-cut methods in place. There are several reasons for becoming addicted to cocaine. Some include chemical dependency, changes in the brain, environmental factors, and familial issues. The list goes on.
Currently, there are no medications on the market that are proven to be effective in weaning people off of cocaine. In the past, researchers have found that cocaine misuse causes fluctuations in brain chemicals such as serotonin, dopamine, and glutamate. To counteract these changes and combat cocaine dependency researches are continually developing supplements that can stabilise these chemicals.
Some medications that are used to treat other diseases have shown some positive results. The drug, disulfiram, which is used to treat alcohol dependency is one of them. Scientists found that disulfiram can inhibit an enzyme that converts dopamine to norepinephrine. Despite the promising results, the drug isn't effective for everyone.
New studies have found that cannabidiol, otherwise known as CBD, is effective in treating cocaine addiction. No trials have been administered with humans as of yet, however, the study shows promising results in mice.
CBD reduces the desire for cocaine
The Pharmacology Biochemistry and Behavior journal recently published a review which examined 14 different studies that were conducted over the last 5 years. Each study was aimed at discovering the potential benefits and effectiveness of CBD reducing cocaine addiction in mice.
In order to study the benefits of CBD researchers presented cocaine to mice and allowed them to consume it as they pleased. Inevitably these mice developed a dependency for cocaine over the course of the study. Subsequently, CBD was introduced to some of the mice to establish if it had the ability to wean them off of the cocaine.
One of the studies that were conducted in 2018 found that mice desired less cocaine when they were given a daily dose of CBD. In the following study mice that had 10 to 20 milligrams of CBD became less interested in cocaine.
These doses significantly increased the threshold for self-stimulation, suggesting a reduction in the brain-stimulation reward.Authors of the study
Researchers concluded that CBD was effective by interfering with cocaine brain reward stimulation and the release of dopamine. In addition to decreasing the desire to consume cocaine, CBD was also helpful in diminishing the negative side-effects of continual cocaine use.
Before concluding that CBD is the ticket for treating cocaine addiction, human trials will need to be conducted.
CBD is slowly becoming an ingredient that can be used to treat all kinds of ailments and addictions. One study indicated that CBD is even effective in reducing cigarette consumption. More recently another study found that CBD may even help the recovery from COVID-19.
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